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Refining the Correa cascade: Gastric stem cell plasticity, niche remodelling, and parallel pathways to neoplasia

Gastric cancer remains a leading cause of cancer mortality. The Correa cascade—stepwise progression from inflammation through atrophic gastritis, metaplasia and dysplasia to adenocarcinoma—has long defined its pathogenesis. Lineage tracing, single-cell multi-omics and organoid models now reveal mark...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Tai Zhang, Zheng Wang, Beihua Zhang, Xudong Tang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2026-08-01
Schriftenreihe:Pharmacological Research
Schlagworte:
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S1043661826002306
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