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HDAC6 dysfunction contributes to impaired maturation of adult neurogenesis in vivo: vital role on functional recovery after ischemic stroke

Abstract Background Promoting post-stroke neurogenesis has long been proposed to be a therapeutic strategy for the enhancement of functional recovery after cerebral ischemic stroke. Despite numerous approaches have been widely reported the proliferation or differentiation of the neurogenic populatio...

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Principais autores: Joen-Rong Sheu, Cheng-Ying Hsieh, Thanasekaran Jayakumar, Guan-Yi Lin, Hsing-Ni Lee, Shin-Wei Huang, Chih-Hao Yang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-04-01
Serier:Journal of Biomedical Science
Fag:
Adult neurogenesis
Histone deacetylase 6
Ischemic stroke
Rehabilitation therapy
Retroviral labeling
Online adgang:http://link.springer.com/article/10.1186/s12929-019-0521-1
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