Gene profiling of postnatal Mfrprd6 mutant eyes reveals differential accumulation of Prss56, visual cycle and phototransduction mRNAs.

Mutations in the membrane frizzled-related protein (MFRP/Mfrp) gene, specifically expressed in the retinal pigment epithelium (RPE) and ciliary body, cause nanophthalmia or posterior microphthalmia with retinitis pigmentosa in humans, and photoreceptor degeneration in mice. To better understand MFRP...

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Huvudupphov:	Ramani Soundararajan, Jungyeon Won, Timothy M Stearns, Jeremy R Charette, Wanda L Hicks, Gayle B Collin, Jürgen K Naggert, Mark P Krebs, Patsy M Nishina
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Public Library of Science (PLoS) 2014-01-01
Serie:	PLoS ONE
Länkar:	https://doi.org/10.1371/journal.pone.0110299
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