Lipid metabolism of clear cell renal cell carcinoma predicts survival and affects intratumoral CD8 T cells

Background: Clear cell renal cell carcinoma (ccRCC), the most common RCC subtype, both accumulates and depletes selected lipid species. However, the prognostic role of lipid metabolic reprogramming in ccRCC has not been studied in detail so far. In addition, ccRCC can show a dense immune infiltratio...

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Autori principali:	Jakob Simeth, Simon Engelmann, Roman Mayr, Sebastian Kaelble, Florian Weber, Renate Pichler, Katja Dettmer, Peter J Oefner, Marcus Höring, Luisa Symeou, Katharina Freitag, Kilian Wagner, Maximilian Burger, Wolfgang Herr, Marina Kreutz, Rainer Spang, Gerhard Liebisch, Peter J Siska
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-11-01
Serie:	Translational Oncology
Soggetti:	Lipids Metabolism Renal cell carcinoma Oncoimmunology T cell Prognosis
Accesso online:	http://www.sciencedirect.com/science/article/pii/S193652332500244X
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