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Effects of TP53 Mutations and miRs on Immune Responses in the Tumor Microenvironment Important in Pancreatic Cancer Progression

Approximately 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC). PDAC is the fourth leading cause of cancer death world-wide. Therapies for PDAC are largely ineffective due to the dense desmoplastic tumor microenvironment which prevents chemotherapeutic drugs and small molecule...

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Principais autores: James A. McCubrey, Li V. Yang, Stephen L. Abrams, Linda S. Steelman, Matilde Y. Follo, Lucio Cocco, Stefano Ratti, Alberto M. Martelli, Giuseppa Augello, Melchiorre Cervello
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2022-07-01
סדרה:Cells
נושאים:
TP53
KRas
PDAC
immunotherapy
miRs
ncRNAs
גישה מקוונת:https://www.mdpi.com/2073-4409/11/14/2155
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