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Study on bioequivalence and influence of obesity-related indicators on pharmacokinetics and pharmacodynamics for insulin degludec in healthy subjects

Abstract This study aimed to evaluate the bioequivalence between test and reference insulin degludec (IDeg) and the effects of body composition on pharmacokinetics and pharmacodynamics of IDeg in Chinese healthy volunteers. In this randomized, open-label, crossover trial, 30 healthy Chinese males we...

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Principais autores: Rui Su, Lei Wan, Yi Tao, Mingxue Zhu, Junliang Pu, Zhongping Li, Yuan Chen, Chengyong Tang
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2024-10-01
Series:Scientific Reports
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Acceso en liña:https://doi.org/10.1038/s41598-024-75554-3
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