Recruitment of the m6A/m6Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48

Abstract Background N6-methyladenosine (m6A), the most abundant internal modification on eukaryotic mRNA, and N6, 2′-O-dimethyladenosine (m6Am), are epitranscriptomic marks that function in multiple aspects of posttranscriptional regulation. Fat mass and obesity-associated protein (FTO) can remove b...

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Autors principals:	Syed Nabeel-Shah, Shuye Pu, Giovanni L. Burke, Nujhat Ahmed, Ulrich Braunschweig, Shaghayegh Farhangmehr, Hyunmin Lee, Mingkun Wu, Zuyao Ni, Hua Tang, Guoqing Zhong, Edyta Marcon, Zhaolei Zhang, Benjamin J. Blencowe, Jack F. Greenblatt
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-09-01
Col·lecció:	Genome Biology
Matèries:	TZAP ZBTB48 MRNA modification M6A/m6Am FTO ICLIP
Accés en línia:	https://doi.org/10.1186/s13059-024-03392-7
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