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Immunohistochemical detection of p53 and pp53 Ser392 in canine hemangiomas and hemangiosarcomas located in the skin

Abstract Background p53 protein is essential for the regulation of cell proliferation. Aberrant accumulation of it usually occurs in cutaneous malignancies. Mutant p53 is detected by immunohistochemistry because it is more stable than the wild-type p53. However, post-translational modifications of p...

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Autores principales: María José García-Iglesias, Jose Luis Cuevas-Higuera, Ana Bastida-Sáenz, María Gracia de Garnica-García, Laura Polledo, Paula Perero, Jorge González-Fernández, Beatriz Fernández-Martínez, Claudia Pérez-Martínez
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2020-07-01
Colección:BMC Veterinary Research
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Acceso en línea:http://link.springer.com/article/10.1186/s12917-020-02457-6
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