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α-Synuclein-Targeted Immunotherapies in Parkinson’s Disease: In Silico, In Vitro and Clinical Perspectives

α-synuclein (α-syn) aggregation in dopaminergic neurons is a central event in Parkinson’s disease (PD) pathogenesis. Immunotherapeutic strategies targeting α-syn, including passive and active approaches, aim to inhibit aggregation, propagation, and toxicity of pathological species while promoting th...

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Hoofdauteurs: Tatiane B. Santos, Tatiane de O. X. Machado, Pedro Henrique S. Rodrigues, Willamys S. Correa, Helena A. C. Kodel, Klebson S. Santos, Margarete Z. Gomes
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2026-06-01
Reeks:Molecules
Onderwerpen:
α-synuclein
immunotherapy
Parkinson’s disease
Online toegang:https://www.mdpi.com/1420-3049/31/12/2036
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