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Mechanism of U6 snRNA oligouridylation by human TUT1

Abstract U6 snRNA is a catalytic RNA responsible for pre-mRNA splicing reactions and undergoes various post-transcriptional modifications during its maturation process. The 3'-oligouridylation of U6 snRNA by the terminal uridylyltransferase, TUT1, provides the Lsm-binding site in U6 snRNA for U4/U6...

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Bibliografische gegevens
Hoofdauteurs: Seisuke Yamashita, Kozo Tomita
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2023-08-01
Reeks:Nature Communications
Online toegang:https://doi.org/10.1038/s41467-023-40420-9
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