A novel chemical-combination screen in zebrafish identifies epigenetic small molecule candidates for the treatment of Duchenne muscular dystrophy

Abstract Background Duchenne muscular dystrophy (DMD) is a severe neuromuscular disorder and is one of the most common muscular dystrophies. There are currently few effective therapies to treat the disease, although many small-molecule approaches are being pursued. Certain histone deacetylase inhibi...

Повний опис

Бібліографічні деталі

Автори:	Gist H. Farr, Melanie Morris, Arianna Gomez, Thao Pham, Elisabeth Kilroy, Elizabeth U. Parker, Shery Said, Clarissa Henry, Lisa Maves
Формат:	Artigo
Мова:	Inglês
Опубліковано:	BMC 2020-10-01
Серія:	Skeletal Muscle
Предмети:	Chemical screen Duchenne muscular dystrophy Epigenetic small molecules HDAC inhibitors Zebrafish
Онлайн доступ:	http://link.springer.com/article/10.1186/s13395-020-00251-4
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!