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Endometriosis-associated infertility alters the microRNA signatures of cumulus cells with a particularly pronounced effect in oocytes that failed fertilization

Abstract Background Endometriosis (E) is multifactorial disease affecting around 10% of women worldwide. The association between E and infertility is clinically well recognized. For E patients to achieve a successful pregnancy, assisted reproductive technologies (ART) are considered as a treatment o...

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Principais autores: Carmen Almiñana, Sofia Makieva, Stefan Bauersachs, Mara D. Saenz-de-Juano, Min Xie, Ana Velasco, Natalia Cervantes, Marianne R. Spalinger, Susanne E. Ulbrich, Brigitte Leeners
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-09-01
Serier:Biological Research
Fag:
Endometriosis-associated infertility
Oocyte quality
Fertilized oocyte
Cumulus cells
miRNAs.
Online adgang:https://doi.org/10.1186/s40659-025-00641-2
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