BRD2 upregulation as a pan-cancer adaptive resistance mechanism to BET inhibition
Abstract Bromodomain and extraterminal motif (BET) inhibitors, such as JQ1, are promising cancer therapeutics that target epigenetic regulators, particularly BRD4. However, resistance to BET inhibitors (BETi) limits their clinical utility, necessitating a better understanding of adaptive mechanisms....
-д хадгалсан:
| Үндсэн зохиолчид: | , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
BMC
2026-05-01
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| Цуврал: | Cellular & Molecular Biology Letters |
| Нөхцлүүд: | |
| Онлайн хандалт: | https://doi.org/10.1186/s11658-026-00922-y |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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