NK cell-specific knockout of UTX modulates pulmonary metastasis of melanoma in a sex-dependent manner

Objective‍　‍To explore the role of X chromosome encoded epigenetic regulator UTX in NK cell-mediated anti-tumor activity. Methods‍　‍Male Ncr1-iCre mice were crossed with female UTXfl/fl mice to generate F1 Ncr1-iCre+UTXfl/- male mice, which were further crossed with female UTXfl/fl mice to obtain ma...

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Bibliografische gegevens
Hoofdauteurs: HUANG Pei, WANG Hongchen, HUANG He
Formaat: Artigo
Taal:Chinês
Gepubliceerd in: Editorial Office of Journal of Army Medical University 2025-04-01
Reeks:陆军军医大学学报
Onderwerpen:
‍pulmonary metastasis
melanoma
nk cells
sex
utx
Online toegang:https://aammt.tmmu.edu.cn/html/202411078.html
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