Pharmacoproteomic characterisation of human colon and rectal cancer

Abstract Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models for proteome‐guided pre‐clinical drug sensitivity studies are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth...

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Autors principals: Martin Frejno, Riccardo Zenezini Chiozzi, Mathias Wilhelm, Heiner Koch, Runsheng Zheng, Susan Klaeger, Benjamin Ruprecht, Chen Meng, Karl Kramer, Anna Jarzab, Stephanie Heinzlmeir, Elaine Johnstone, Enric Domingo, David Kerr, Moritz Jesinghaus, Julia Slotta‐Huspenina, Wilko Weichert, Stefan Knapp, Stephan M Feller, Bernhard Kuster
Format: Artigo
Idioma:Inglês
Publicat: Springer Nature 2017-11-01
Col·lecció:Molecular Systems Biology
Matèries:
CPTAC
CRC65
drug response
patient stratification
proteomics
Accés en línia:https://doi.org/10.15252/msb.20177701
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