Investigating the Disordered and Membrane-Active Peptide A-Cage-C Using Conformational Ensembles

The driving forces and conformational pathways leading to amphitropic protein-membrane binding and in some cases also to protein misfolding and aggregation is the subject of intensive research. In this study, a chimeric polypeptide, A-Cage-C, derived from α-Lactalbumin is investigated with the aim o...

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Detalhes bibliográficos

Principais autores:	Olena Dobrovolska, Øyvind Strømland, Ørjan Sele Handegård, Martin Jakubec, Morten L. Govasli, Åge Aleksander Skjevik, Nils Åge Frøystein, Knut Teigen, Øyvind Halskau
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-06-01
coleção:	Molecules
Assuntos:	oligomerizing peptides bicelles lipids conformation slow exchange ensemble clustering
Acesso em linha:	https://www.mdpi.com/1420-3049/26/12/3607
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