Physiological oxygen concentration during sympathetic primary neuron culture improves neuronal health and reduces HSV-1 reactivation

ABSTRACT Herpes simplex virus-1 (HSV-1) establishes a latent infection in peripheral neurons and periodically reactivates in response to a stimulus to permit transmission. In vitro models using primary neurons are invaluable to studying latent infection because they use bona fide neurons that have u...

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Dades bibliogràfiques

Autors principals:	Sara A. Dochnal, Patryk A. Krakowiak, Abigail L. Whitford, Anna R. Cliffe
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2024-12-01
Col·lecció:	Microbiology Spectrum
Matèries:	herpes simplex virus oxygen in vitro culture latency reactivation sympathetic neurons
Accés en línia:	https://journals.asm.org/doi/10.1128/spectrum.02031-24
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