Characterization of the plant homeodomain (PHD) reader family for their histone tail interactions

Abstract Background Plant homeodomain (PHD) fingers are central “readers” of histone post-translational modifications (PTMs) with > 100 PHD finger-containing proteins encoded by the human genome. Many of the PHDs studied to date bind to unmodified or methylated states of histone H3 lysine 4 (H3K4)....

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Autori principali:	Kanishk Jain, Caroline S. Fraser, Matthew R. Marunde, Madison M. Parker, Cari Sagum, Jonathan M. Burg, Nathan Hall, Irina K. Popova, Keli L. Rodriguez, Anup Vaidya, Krzysztof Krajewski, Michael-Christopher Keogh, Mark T. Bedford, Brian D. Strahl
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2020-01-01
Serie:	Epigenetics & Chromatin
Soggetti:	Chromatin Histone methylation PHD fingers Histone peptide microarray Protein domain microarray
Accesso online:	https://doi.org/10.1186/s13072-020-0328-z
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