Unsaturated Fatty Acid-Induced Conformational Transitions and Aggregation of the Repeat Domain of Tau

Background: The intrinsically disordered, amyloidogenic protein Tau associates with diverse classes of molecules, including proteins, nucleic acids, and lipids. Mounting evidence suggests that fatty acid molecules could play a role in the dysfunction of this protein, however, their interaction with...

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Prif Awduron:	Carlo Giorgio Barracchia, Roberto Tira, Francesca Parolini, Francesca Munari, Luigi Bubacco, Georgios A. Spyroulias, Mariapina D’Onofrio, Michael Assfalg
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2020-06-01
Cyfres:	Molecules
Pynciau:	fatty acids neurodegeneration NMR spectroscopy protein–lipid interactions protein aggregation Tau
Mynediad Ar-lein:	https://www.mdpi.com/1420-3049/25/11/2716
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!