Synthesis of a novel coumarin via the Mannich reaction: in vitro and in silico evaluation of anti-cancer, antimicrobial and antioxidant activities
The novel coumarin derivatives (2a–2j) were synthesized via the Mannich reaction and evaluated for anti-cancer, antimicrobial and antioxidant activities. Compound (2d) exhibited the most potent cytotoxicity against MCF-7 breast cancer cells (IC50 = 2.54 ± 0.12 µM), surpassing camptothecin. Compound...
Kaydedildi:
| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Royal Society
2025-10-01
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| Seri Bilgileri: | Royal Society Open Science |
| Konular: | |
| Online Erişim: | https://royalsocietypublishing.org/doi/10.1098/rsos.250854 |
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