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High HBsAg clearance rate and viral dynamics in HBeAg-positive, ALT-normal children and adolescents with chronic HBV infection: results from the prospective sprout project

Hepatitis B e antigen (HBeAg)-positive chronic hepatitis B virus (HBV) infection in children and adolescents with normal alanine aminotransferase (ALT) levels constitutes a substantial population in China, yet the optimal timing for antiviral therapy remains unclear. This prospective, real-world stu...

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Principais autores: Xin Wang, Changxiang Lai, Ruiling Li, Jia Lei, Yuyin Xie, Zhiyu Li, Qiyuan Tang, Qing He, Hongfei Zhang, Zheng Zhang, Fang Wang
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2025-12-01
Serier:Emerging Microbes and Infections
Fag:
Chronic hepatitis B
immune-tolerant
grey zone
PEG-IFN-α
HBsAg loss
Online adgang:https://www.tandfonline.com/doi/10.1080/22221751.2025.2516173
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