Antisense Activity across the Nesp Promoter is Required for Nespas-Mediated Silencing in the Imprinted Gnas Cluster
Macro long non-coding RNAs (lncRNAs) play major roles in gene silencing in inprinted gene clusters. Within the imprinted Gnas cluster, the paternally expressed Nespas lncRNA downregulates its sense counterpart Nesp. To explore the mechanism of action of Nespas, we generated two new knock-in alleles...
Gardado en:
| Principais autores: | , , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI AG
2015-11-01
|
| Series: | Non-Coding RNA |
| Assuntos: | |
| Acceso en liña: | http://www.mdpi.com/2311-553X/1/3/246 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|