Linker histone H1 represses H3 tail acetylation induced by H4 tail acetylation and alters its dynamics

Abstract The nucleosome is the fundamental chromatin unit, containing two copies of histones H2A, H2B, H3, and H4 wrapped by ~ 146 bp of core DNA plus linker DNA; addition of linker histone H1 forms a chromatosome. Tetra-acetylation of the H4 N-terminal tail (H4-4Kac) enhances H3 N-tail acetylation...

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Detalhes bibliográficos

Principais autores:	Ayako Furukawa, Kenta Echigoya, Samuel Blazquez, Masatoshi Wakamori, Hideaki Ohtomo, Yasuo Tsunaka, Takashi Umehara, Tsuyoshi Terakawa, Yoshimasa Takizawa, Hitoshi Kurumizaka, Yoshifumi Nishimura
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-04-01
coleção:	Communications Biology
Acesso em linha:	https://doi.org/10.1038/s42003-026-09926-y
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