POLD1 Mutations May be Effective Predictive Biomarker for the Response to Durvalumab plus Gemcitabine and Cisplatin in Metastatic Cholangiocarcinoma: A Case Report

Biliary tract cancers have a poor prognosis with limited treatment options. While immune checkpoint inhibitors have recently shown modest survival benefits as standard first-line therapy, reliable predictive biomarkers for the response to treatment remain lacking. This case report describes a 61-yea...

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Bibliografische Detailangaben

Hauptverfasser:	Seh-Hian Ng, Hsueh-Ju Lu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wolters Kluwer Medknow Publications 2025-10-01
Schriftenreihe:	Journal of Cancer Research and Practice
Schlagworte:	biliary tract cancer case report immune checkpoint inhibitors pole/pold1 predictive biomarker
Online-Zugang:	https://journals.lww.com/10.4103/ejcrp.eJCRP-D-25-00028
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