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BCMA (TNFRSF17) Induces APRIL and BAFF Mediated Breast Cancer Cell Stemness

Recent advances in cancer immunology revealed immune-related properties of cancer cells as novel promising therapeutic targets. The two TNF superfamily members, APRIL (TNFSF13), and BAFF (TNFSF13B), which are type II membrane proteins, released in active forms by proteolytic cleavage and are primari...

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Principais autores: Vasiliki Pelekanou, George Notas, Paraskevi Athanasouli, Konstantinos Alexakis, Fotini Kiagiadaki, Nikolaos Peroulis, Konstantina Kalyvianaki, Errika Kampouri, Hara Polioudaki, Panayiotis Theodoropoulos, Andreas Tsapis, Elias Castanas, Marilena Kampa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-08-01
coleção:Frontiers in Oncology
Assuntos:
APRIL (TNFSF13)
BAFF (TNFSF13B)
BCMA (TNFRSF17)
pluripotency
cancer stem cells
therapy resistance
Acesso em linha:https://www.frontiersin.org/article/10.3389/fonc.2018.00301/full
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