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DNA methylation patterns facilitate tracing the origin of neuroendocrine neoplasms

Abstract Neuroendocrine neoplasms (NEN) are thought to originate from diffuse neuroendocrine networks and therefore most frequently arise in the gastrointestinal tract and lungs. The liver is a frequent site of metastasis of NEN but also the existence of primary hepatic NEN has been proposed. Due to...

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Autori principali: Benjamin Goeppert, Alphonse Charbel, Reka Toth, Yue Zhang, Danial Tabbakh, Thomas Albrecht, Daniel Schrimpf, Louis de Mestier, Jérôme Cros, Monika Nadja Vogel, De-Hua Chang, Eva-Marie Bohn, Alexander Brobeil, Junfang Ji, Stephan Singer, Petr V. Nazarov, Aurel Perren, Leonidas Apostolidis, Andreas von Deimling, Stephanie Roessler
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-10-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-025-65227-8
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