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LOX-1 augments oxLDL uptake by lysoPC-stimulated murine macrophages but is not required for oxLDL clearance from plasma

Oxidized LDL (oxLDL) promotes lipid accumulation as well as growth and survival signaling in macrophages. OxLDL uptake is mainly due to scavenger receptors SR-AI/II and CD36. However, other scavenger receptors such as lectin-like oxLDL receptor-1 (LOX-1) may also play a role. We used mice with targe...

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Bibliografiske detaljer
Principais autores: David F. Schaeffer, Maziar Riazy, Kuljit S. Parhar, Johnny H. Chen, Vincent Duronio, Tatsuya Sawamura, Urs P. Steinbrecher
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2009-08-01
Serier:Journal of Lipid Research
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Online adgang:http://www.sciencedirect.com/science/article/pii/S0022227520307689
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