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The effect of closed-loop glucose control on C-peptide secretion in youth with newly diagnosed type 1 diabetes: the CLOuD RCT

Background We assessed whether a sustained period of intensive glucose control with hybrid closed-loop for 12 months following diagnosis of type 1 diabetes in children and adolescents can preserve C-peptide secretion compared to standard insulin therapy. Methods In an open-label, multicentre, random...

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Detalles Bibliográficos
Principais autores: Charlotte K Boughton, Janet M Allen, Julia Ware, Malgorzata E Wilinska, Sara Hartnell, Ajay Thankamony, Tabitha Randell, Atrayee Ghatak, Rachel EJ Besser, Daniela Elleri, Nicola Trevelyan, Fiona M Campbell, David Rankin, Barbara Kimbell, Julia Lawton, Judy Sibayan, Peter Calhoun, Ryan Bailey, Gareth Dunseath, Roman Hovorka
Formato: Artigo
Idioma:Inglês
Publicado: NIHR Journals Library 2024-05-01
Series:Efficacy and Mechanism Evaluation
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Acceso en liña:https://doi.org/10.3310/KTFR5698
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