Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15

Summary: Introduction of fetal cell cycle genes into damaged adult hearts has emerged as a promising strategy for stimulating proliferation and regeneration of postmitotic adult cardiomyocytes. We have recently identified Fam64a as a fetal-specific cell cycle promoter in cardiomyocytes. Here, we ana...

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Autores principales:	Ken Hashimoto, Aya Kodama, Momoko Ohira, Misaki Kimoto, Reiko Nakagawa, Yuu Usui, Yoshihiro Ujihara, Akira Hanashima, Satoshi Mohri
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2022-05-01
Colección:	iScience
Materias:	Biological sciences Cell biology Stem cells research
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2589004222006083
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