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Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection.

Effective T cell responses can decisively influence the outcome of retroviral infection. However, what constitutes protective T cell responses or determines the ability of the host to mount such responses is incompletely understood. Here we studied the requirements for development and induction of C...

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Autors principals: George R Young, Mickaël J-Y Ploquin, Urszula Eksmond, Munisch Wadwa, Jonathan P Stoye, George Kassiotis
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS Pathogens
Accés en línia:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002709&type=printable
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