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Embryonic stem cells are redirected to non-tumorigenic epithelial cell fate by interaction with the mammary microenvironment.

Experiments were conducted to redirect mouse Embryonic Stem (ES) cells from a tumorigenic phenotype to a normal mammary epithelial phenotype in vivo. Mixing LacZ-labeled ES cells with normal mouse mammary epithelial cells at ratios of 1:5 and 1:50 in phosphate buffered saline and immediately inocula...

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Збережено в:
Бібліографічні деталі
Автори: Corinne A Boulanger, Robert D Bruno, David L Mack, Monica Gonzales, Nadia P Castro, David S Salomon, Gilbert H Smith
Формат: Artigo
Мова:Inglês
Опубліковано: Public Library of Science (PLoS) 2013-01-01
Серія:PLoS ONE
Онлайн доступ:http://europepmc.org/articles/PMC3637449?pdf=render
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