Convergent epigenetic evolution drives relapse in acute myeloid leukemia
Relapse of acute myeloid leukemia (AML) is highly aggressive and often treatment refractory. We analyzed previously published AML relapse cohorts and found that 40% of relapses occur without changes in driver mutations, suggesting that non-genetic mechanisms drive relapse in a large proportion of ca...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications Ltd
2024-04-01
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| Serija: | eLife |
| Teme: | |
| Online pristup: | https://elifesciences.org/articles/93019 |
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