A Goldilocks Principle for the Gut Microbiome: Taxonomic Resolution Matters for Microbiome-Based Classification of Colorectal Cancer

ABSTRACT Colorectal cancer is a common and deadly disease in the United States accounting for over 50,000 deaths in 2020. This progressive disease is highly preventable with early detection and treatment, but many people do not comply with the recommended screening guidelines. The gut microbiome has...

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Hauptverfasser:	Courtney R. Armour, Begüm D. Topçuoğlu, Andrea Garretto, Patrick D. Schloss
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2022-02-01
Schriftenreihe:	mBio
Schlagworte:	16S rRNA gene sequencing colon cancer machine learning microbiome taxonomic level
Online-Zugang:	https://journals.asm.org/doi/10.1128/mbio.03161-21
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