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Structure of a bacterial RNA polymerase holoenzyme open promoter complex

Initiation of transcription is a primary means for controlling gene expression. In bacteria, the RNA polymerase (RNAP) holoenzyme binds and unwinds promoter DNA, forming the transcription bubble of the open promoter complex (RPo). We have determined crystal structures, refined to 4.14 Å-resolution,...

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Principais autores: Brian Bae, Andrey Feklistov, Agnieszka Lass-Napiorkowska, Robert Landick, Seth A Darst
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications Ltd 2015-09-01
Series:eLife
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Acceso en liña:https://elifesciences.org/articles/08504
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