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The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission.

Infection of red blood cells (RBC) subjects the malaria parasite to oxidative stress. Therefore, efficient antioxidant and redox systems are required to prevent damage by reactive oxygen species. Plasmodium spp. have thioredoxin and glutathione (GSH) systems that are thought to play a major role as...

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Библиографические подробности
Главные авторы: Joel Vega-Rodríguez, Blandine Franke-Fayard, Rhoel R Dinglasan, Chris J Janse, Rebecca Pastrana-Mena, Andrew P Waters, Isabelle Coppens, José F Rodríguez-Orengo, Prakash Srinivasan, Marcelo Jacobs-Lorena, Adelfa E Serrano
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2009-02-01
Серии:PLoS Pathogens
Online-ссылка:https://doi.org/10.1371/journal.ppat.1000302
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