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High hemolytic activity in Staphylococcus aureus t1081/ST45 due to increased hla protein production and potential RNAIII-independent regulation

Background: α-Hemolysin, encoded by hla, is a major virulence factor of Staphylococcus aureus. Sequence type (ST) 45 is a globally spread clone with increasing clinical prevalence in Taiwan. Our previous study showed that among the CC45 isolates, the spa type t1081 isolates presented greater hemolyt...

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Principais autores: Yu-Tzu Lin, Ngoc-Niem Bui, Yu-Syuan Cheng, Cheng-Wen Lin, Chun-Li Lee, Tai-Fen Lee, Po-Ren Hsueh
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2025-02-01
Series:Journal of Microbiology, Immunology and Infection
Assuntos:
t1081
ST45
Hemolytic activity
α-hemolysin
Hla
RNAIII-Independent
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S168411822400183X
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