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Engineered oncolytic virus for the treatment of cholesteatoma: A pilot in vivo study

Objective Determine if oncolytic herpes simplex virus (oHSV) can eradicate cholesteatoma (CHST) in a gerbil model. Methods An in vivo model of CHST was developed in Mongolian gerbils by combining Pseudomonas aeruginosa inoculation with double ligation of the external auditory canal (EAC). CHST size...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Ravi N. Samy, Brian R. Earl, Noga Lipschitz, Ivy Schweinzger, Mark Currier, Timothy Cripe
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Wiley 2019-10-01
Rangatū:Laryngoscope Investigative Otolaryngology
Ngā marau:
Urunga tuihono:https://doi.org/10.1002/lio2.307
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