Rethinking TYK2 P1104A: a flawed evolutionary trade-off in tuberculosis?
The TYK2 P1104A variant has been cast as a textbook example of evolutionary compromise-protecting against autoimmunity whilst increasing susceptibility to tuberculosis (TB). This narrative has been invoked to explain its decline in frequency in European populations since the Bronze Age. However, acc...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2026-06-01
|
| Schriftenreihe: | Frontiers in Immunology |
| Schlagworte: | |
| Online-Zugang: | https://www.frontiersin.org/articles/10.3389/fimmu.2026.1845279/full |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|