Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei.

All cells are subject to structural damage that must be addressed for continued growth. A wide range of damage affects the genome, meaning multiple pathways have evolved to repair or bypass the resulting DNA lesions. Though many repair pathways are conserved, their presence or function can reflect t...

Descrición completa

Detalles Bibliográficos

Principais autores:	Jennifer A Stortz, Tiago D Serafim, Sam Alsford, Jonathan Wilkes, Fernando Fernandez-Cortes, Graham Hamilton, Emma Briggs, Leandro Lemgruber, David Horn, Jeremy C Mottram, Richard McCulloch
Formato:	Artigo
Idioma:	Inglês
Publicado:	Public Library of Science (PLoS) 2017-07-01
Series:	PLoS Pathogens
Acceso en liña:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006477&type=printable
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!