Ursodeoxycholic acid alleviates aortic aneurysm and dissection through the intestinal farnesoid X receptor/ceramide synthase 2 axis

Abstract Aortic aneurysm and dissection (AAD) are severe cardiovascular conditions that carry significant risks and currently lack an effective treatment. Ursodeoxycholic acid (UDCA) can delay the onset of various metabolic diseases such as type 2 diabetes and obesity. However, it remains unclear wh...

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मुख्य लेखकों:	Zhaofeng Zhang, Linfeng Xie, Xinfan Lin, Jian He, Yuling Xie, Jiakang Li, Xinghui Zhuang, Lele Tang, Rumei Xie, Qingsong Wu, Zhihuang Qiu, Liangwan Chen
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Nature Portfolio 2025-07-01
श्रृंखला:	Communications Biology
ऑनलाइन पहुंच:	https://doi.org/10.1038/s42003-025-08403-2
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