Multifunctional vitamin D-incorporated PLGA scaffold with BMP/VEGF-overexpressed tonsil-derived MSC via CRISPR/Cas9 for bone tissue regeneration

Guiding endogenous regeneration of bone defects using biomaterials and regenerative medicine is considered an optimal strategy. One of the effective therapeutic approaches involves using transgene-expressed stem cells to treat tissue destruction and replace damaged parts. Among the various gene edit...

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Principais autores:	So-Yeon Park, Jun-Kyu Lee, Sang-Hyeok Lee, Da-Seul Kim, Ji-Won Jung, Jun Hyuk Kim, Seung-Woon Baek, Seungkwon You, Dong-Youn Hwang, Dong Keun Han
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2024-10-01
Series:	Materials Today Bio
Assuntos:	CRISPR Cas9 Vitamin D PLGA scaffold BMP2/VEGF-Overexpression Tonsil-derived MSC
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2590006424003156
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