Pan-cancer analysis of CHRDL1 expression and its mechanistic role in inhibiting EMT via the TGF-β pathway in lung adenocarcinoma

BackgroundThe primary objective of this study is to conduct a pan-cancer analysis of CHRDL1 expression, to determine its correlation with patient survival rates, immune cell infiltration, and drug sensitivity. Additionally, the study aimed to further validate the mechanistic role of CHRDL1 in lung a...

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Hlavní autoři:	Honghong Dong, Yahui Tian, Shaowei Xin, Yujie Guo, Suxin Jiang, Zitong Wan, Huaiyu Wang, Yong Han
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-03-01
Edice:	Frontiers in Cell and Developmental Biology
Témata:	Chrdl1 lung adenocarcinoma pan-cancer analysis Epithelialmesenchymal transition TGF-β pathway immune infiltration
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1557761/full
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