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Development and design of CRISPR-based diagnostic for Acinetobacter baumannii by employing off-target gene editing of sgRNA

Acinetobacter baumannii is widely recognized as a human opportunistic pathogen in nosocomial infections. The proliferation of multidrug-resistant strains of A. baumannii has presented an array of difficulties for clinical anti-infective therapies and diagnostic procedures, owing to the existence of...

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Principais autores: Zulqarnain Baqar, Sk Injamamul Islam, Gunjan Das, Sarower Mahfuj, Foysal Ahammad
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-01-01
coleção:Informatics in Medicine Unlocked
Assuntos:
CRISPR-Cas
Off-targets
sgRNA
Diagnosis
Plasmid
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352914824000182
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