Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation

Abstract Background Phosphatase and tensin homolog deleted on chromosome ten (PTEN) serves as a powerful tumor suppressor, and has been found to be downregulated in human bladder cancer (BC) tissues. Despite this observation, the mechanisms contributing to PTEN’s downregulation have remained elusive...

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Hauptverfasser:	Tengda Li, Maowen Huang, Ning Sun, Xiaohui Hua, Ruifan Chen, Qipeng Xie, Shirui Huang, Mengxiang Du, Yazhen Zhao, Qianqian Lin, Jiheng Xu, Xiaoyun Han, Yunping Zhao, Zhongxian Tian, Yu Zhang, Wei Chen, Xian Shen, Chuanshu Huang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-02-01
Schriftenreihe:	Journal of Experimental & Clinical Cancer Research
Schlagworte:	lncRNA SNHG1 PTEN USP8 Bladder cancer
Online-Zugang:	https://doi.org/10.1186/s13046-024-02966-4
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