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Enhancing T cell infiltration in glioblastoma: a review article on challenges and therapeutic strategies

This review focuses on enhancing T-cell infiltration in glioblastoma (GBM) while overcoming its immunosuppressive tumor microenvironment (TME). Key strategies include targeting myeloid-derived suppressor cells (MDSCs) to reduce immunosuppression and repolarizing tumor-associated macrophages (TAMs) f...

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Kaydedildi:
Asıl Yazarlar: Mohammad Amin Habibi, Negar Nejati, Majed Bahri Najafi, Alireza Khodadadiyan, Mohsen Dashti, Parsa Lorestani, Zahra Karimizadeh, Mahsa Ahmadpour, Amirali Kalantari, Armita Jokar-Derisi, Faezeh Maghsood, Behrouz Robat-Jazi, Elaheh Ebrahimi, Sajjad Ahmadpour, Soheil Tavakolpour
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2025-01-01
Seri Bilgileri:Cancer Treatment and Research Communications
Konular:
Glioblastoma
Immunotherapy
Tumor microenvironment
Blood–brain barrier
Tumor-infiltrating lymphocytes
Immunosuppressive microenvironment
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2468294225001352
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