Long term behavior of dexamethasone-loaded cochlear implants: In vitro & in vivo

The aim of this study was to better understand the long term behavior of silicone-based cochlear implants loaded with dexamethasone: in vitro as well as in vivo (gerbils). This type of local controlled drug delivery systems offers an interesting potential for the treatment of hearing loss. Because v...

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Autors principals:	T. Rongthong, A. Qnouch, M. Maue Gehrke, F. Danede, J.F. Willart, P.F.M. de Oliveira, L. Paccou, G. Tourrel, P. Stahl, J. Verin, P. Toulemonde, C. Vincent, F. Siepmann, J. Siepmann
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2022-12-01
Col·lecció:	International Journal of Pharmaceutics: X
Matèries:	Cochlear implant Dexamethasone Silicone Raman imaging Diffusion
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2590156722000329
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