Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse

Microglia, the resident immune cells of the brain parenchyma, are highly responsive to tissue injury. Following cell damage, microglial processes redirect their motility from randomly scouting the extracellular space to specifically reaching toward the compromised tissue. While the cell morphology a...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Amir ePozner, Ben eXu, Sierra ePalumbos, J. Michael Gee, Petr eTvrdik, Mario R. Capecchi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2015-05-01
Schriftenreihe:	Frontiers in Molecular Neuroscience
Schlagworte:	Microglia GECI calcium imaging purinergic receptors GCaMP5G PC::G5-tdT
Online-Zugang:	http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00012/full
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