Exogenous butyrate inhibits butyrogenic metabolism and alters virulence phenotypes in Clostridioides difficile

ABSTRACT The gut microbiome engenders colonization resistance against the diarrheal pathogen Clostridioides difficile, but the molecular basis of this colonization resistance is incompletely understood. A prominent class of gut microbiome-produced metabolites important for colonization resistance ag...

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Autors principals:	Daniel A. Pensinger, Horia A. Dobrila, David M. Stevenson, Nicole D. Hryckowian, Daniel Amador-Noguez, Andrew J. Hryckowian
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2024-03-01
Col·lecció:	mBio
Matèries:	pathogenesis enteric pathogens gram-positive bacteria metabolism
Accés en línia:	https://journals.asm.org/doi/10.1128/mbio.02535-23
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