A unique role for IL-13 in inducing esophageal eosinophilia through MID-1 and STAT6

IntroductionEosinophilic esophagitis (EoE) is associated with allergen-driven inflammation of the esophagus and an upregulated Th2 cytokine signature. Recombinant interleukin (IL)-13 (rIL-13) administration to mice induces some of the hallmark features of EoE, including increased eotaxin expression...

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Principais autores:	Jason L. N. Girkin, Leon A. Sokulsky, Malcolm R. Starkey, Philip M. Hansbro, Paul S. Foster, Adam M. Collison, Joerg Mattes
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2023-11-01
סדרה:	Frontiers in Allergy
נושאים:	eosinophils eosinophilic esophagitis allergy interleukin 13 (IL-13) midline 1 (Mid1)
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/falgy.2023.1248432/full
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