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Aberrant gene expression and sexually incompatible genomic imprinting in oocytes derived from XY mouse embryonic stem cells in vitro.

Mouse embryonic stem cells (ESCs) have the potential to differentiate into germ cells (GCs) in vivo and in vitro. Interestingly, XY ESCs can give rise to both male and female GCs in culture, irrespective of the genetic sex. Recent studies showed that ESC-derived primordial GCs contributed to functio...

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Główni autorzy: Mai Nitta, Masanori Imamura, Yu Inoue, Yasuo Kunitomo, Zachary Yu-Ching Lin, Takuya Ogawa, Keiichiro Yogo, Norihiro Ishida-Kitagawa, Noritaka Fukunaga, Hideyuki Okano, Eimei Sato, Tatsuo Takeya, Jun Miyoshi
Format: Artigo
Język:Inglês
Wydane: Public Library of Science (PLoS) 2013-01-01
Seria:PLoS ONE
Dostęp online:http://europepmc.org/articles/PMC3589367?pdf=render
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